Below are details on the various committees, processes, and documents that govern the working of the Genomics England Clinical Interpretation Partnership (GeCIP).
GeCIP Boards and Committees
GeCIP Board
Chair: Professor Dame Kay Davies
The GeCIP Board is tasked with overseeing and steering GeCIP. It acts as a focus for co-ordination of GeCIP activities, including aspects of strategy and disease area or funding opportunities and meets twice a year.
It is comprised of:
- representatives from funders (National Institute for Health Research, Wellcome Trust, Medical Research Council, Cancer Research UK);
- a representative from the Genomics England Scientific Advisory Committee;
- the Genomics England Chief Scientist, Prof Mark Caulfield;
- a patient representative;
- and a representative from each of the Cancer, Rare Diseases, and Cross-Cutting arms of GeCIP, as decided by the GeCIP Steering Committee.
Visit the GeCIP Board page with membership details and meeting minutes
GeCIP Steering Committee
Chair: Genomics England Chief Scientist, Prof Mark Caulfield
The GeCIP Steering Committee is a subcommittee of the GeCIP Board and is comprised of representatives from each of the different domains. For convenience, it has been split into three separate sub-committees along the lines of Cancer, Rare Diseases, and Cross-Cutting domains. The plan is for these sub committees to meet regularly, and for there to be a single meeting each year where all domain representatives meet as one. It's main activities include:
- evaluating reports and plans from the GeCIP and advise the GeCIP Board on the success, functionality or otherwise of the Domains;
- advising the GeCIP Board on the need to form new Domains;
- advising the domains and the GeCIP Board on tasks or work packages to progress the Genomics England programme in a timely and efficient manner according to the Project Plan and associated milestones;
- overseeing and advising on appropriateness of grant plans, authorship or publication plans and membership of Domain.
Visit the GeCIP Steering Committee page with membership details and meeting minutes
Access Review Committee
Chair: Prof Jonathan Knowles
The Access Review Committee (ARC) has been established as a vital advisory body within the 100,000 Genomes Project. The primary purpose of the ARC is to provide an independent examination of requests for data access based on the principles in the Data Access and Acceptable Uses Policy of Genomics England.
The ARC will deliver decisions to approve, decline, or amend requests for access to data. Such decisions are made taking into account factors such as: the nature of the research, the proportionality of the dataset size, and the risk of identifiability. External sources of expertise may be called upon to assist the decision-making process by evaluating the perceived potential risks. This mechanism will be in place to ensure the dataset is being put to responsible research activities.
Visit the Access Review Committee page for more information on data access guidance.
Publication Committee
Scientific Advisory Committee
Chair: Prof Sir John Bell
The Scientific Advisory Committee is commissioned with ensuring the Genomics England has access to the best possible scientific advice. The committee advises on all aspects of the 100,000 Genomes Project and is asked to ratify many aspects of the project from sample collection, through disease or tumour type selection, to the individual GeCIP Domain's research plans.
Cancer Working Group
The Cancer Working Group assembles representatives from each of the Cancer domains, representatives from the GMC community, and various members of Genomics England's Science Team. The group is consulted on various aspects of the cancer programme and provides expert advice on a variety of topics.
>>Visit the Cancer Working Group page with membership details and meeting minutes
Rare Diseases Working Group
The Rare Disease Working Group assembles representatives from each of the Rare Disease domains, representatives from the GMC community, and members of Genomics England's Science Team. The group is consulted on various aspects of the Rare Disease programme and provides expert advice on a variety of topics.
Cross-Cutting Working Group
Currently domain leads and the GeCIP Cross-Cutting co-ordinator will, when appropriate attend working group meetings held by the Cancer Working Group and Rare Diseases Working Group. Cross-Cutting representatives and the GeCIP Cross-Cutting co-ordinator, maintain a standing invitation to attend these meetings as and when they require.